Pregnenolone, the Master Hormone

The Master Hormone

Pregnenolone has been referred to as the mother and balancer of other hormones. First the body converts cholesterol to Pregnenolone. From Pregnenolone, there are two main courses of hormonal synthesis, one toward DHEA and one toward progesterone. Therefore, Pregnenolone is necessary for proper balancing of estrogen, testosterone, DHEA and Pregnenolone, cortical and aldosterone.

Pregnenolone, like DHEA, has been shown in many studies to improve brain functions such as mood, memory and cognition, and to improve mental energy levels, and alertness. These effects may be achieved at quite low doses.

reater doses have had a beneficial role in treating PMS, menopause, stress reduction, immunity, arthritis, and other conditions. Like many other hormones, Pregnenolone production declines greatly with age. It has been estimated that Pregnenolone production declines by 40-55% by age 50.

Pregnenolone has very synergistic effects when taken with DHEA and Melatonin. Appetite is significantly decreased and cravings for alcohol, caffeine, nicotine, mind altering drugs and even chocolate are usually decreased as well. The sense of well-being is increased and the craving for junk foods and harmful substances is decreased or eliminated.

Pregnenolone strengthens the membranes that are vital to the healthy functioning of the central nervous system. Pregnenolone is also important as a precursor for the body’s production of other hormones. Pregnenolone is made by many organs within the body, including the skin, adrenal glands, liver, and the testes and ovaries. It is an important precursor for the production of DHEA and progesterone. These are actually synthesized in the body from Pregnenolone. Therefore, both DHEA and progesterone body levels can be increased by Pregnenolone supplementation.

Pregnenolone is the most potent memory enhancer ever discovered. It enhances our mental performance, facilitates learning, helps us adapt to stress, increases our feeling of well being and actually makes us happier and more appreciative of life. Pregnenolone improves concentration, prevents mental fatigue, increases productivity and keeps our brain functioning at peak capacity.

As a dietary supplement, Pregnenolone is safe at doses between 10 and 100 milligrams per day. The average Pregnenolone production in the body is estimated to be 14 mg per day. Pregnenolone has no known toxicity according to Eugene Roberts, neurobiologist. Reputable researchers such as Ray Peat, Ph.D., can find no misbalancing effect, even with large doses of Pregnenolone.
Pregnenolone administered at 25-50mg doses per day has been effective in combating mental fatigue and improving energy with no side effects. Brain function, including memory, thinking and mood, can be improved by administration of only 20 mg of Pregnenolone every day for two weeks.

Blood levels of Pregnenolone decline with age and may be related to many of the degenerative processes associated with aging. Regular supplementation with Pregnenolone may help prevent the gradually increasing hormonal imbalances associated with many of the symptoms of aging.

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Pregnenolone and DHEA should not be used by young children, teenagers, pregnant or lactating women, or anyone with a medical condition unless under the direct administration of a physician. When supplementing with Pregnenolone, have your DHEA and Pregnenolone levels tested by a health professional. After taking supplements, levels should be re-tested to ensure the maintenance of optimum levels of the hormone.